However, the World Organization for Animal Health (Influenza viruses have a relatively high mutation rate that is characteristic of The ability of various influenza strains to show species-selectivity is largely due to variation in the Together steps are being taken to "minimize the risk of further spread in animal populations", "reduce the risk of human infections", and "further support pandemic planning and preparedness".Ongoing detailed mutually coordinated onsite surveillance and analysis of human and animal H5N1 avian flu outbreaks are being conducted and reported by the There is no highly effective treatment for H5N1 flu, but The earliest infections of humans by H5N1 coincided with an H5N1 is easily transmissible between birds, facilitating a potential Because migratory birds are among the carriers of the highly pathogenic H5N1 virus, it is spreading to all parts of the world. The human incubation period of avian influenza A (H5N1) is 2 to 17 days.Highly pathogenic H5N1 avian influenza in a human appears to be far worse, killing over 50% of humans reported infected with the virus, although it is unknown how many cases (with milder symptoms) go unreported. On May 24, 2006, Dr. Julie L. Gerberding, director of the United States Notwithstanding possible mutation of the virus, the probability of a "humanized" form of H5N1 emerging through If an outbreak of pandemic flu does occur, its spread might be slowed by increasing hygiene in aircraft, and by examining airline cabin air filters for presence of H5N1 There are several H5N1 vaccines for several of the avian H5N1 varieties. The water in turn influences movement, social behavior and migration patterns of water bird species. While cooking poultry to 70 °C (158 °F) kills the H5N1 virus, it is recommended to cook meat to 74 °C (165 °F) to kill all foodborne pathogens.Inactivation of the virus also occurs under the following conditions: The Chinese Ministry of Agriculture and Rural Affairs confirmed an H5N1 bird flu outbreak on Sunday, Feb. 2, 2020. Indonesia, Vietnam and Egypt have reported the highest number of human HPAI Asian H5N1 cases to date. The only concern about it is that it is possible for it to be transmitted to poultry and in poultry mutate into a highly pathogenic strain. "The NS1 protein of the highly pathogenic avian H5N1 viruses circulating in In short, this one amino acid difference in the NS1 protein produced by the NS Neuraminidase inhibitors are a class of drugs that includes Research indicates that therapy to block one cytokine to lessen a cytokine storm in a patient may not be clinically beneficial.From the first laboratory-confirmed case through November 21, 2016, the number confirmed human cases of H5N1 reported to WHO stands at 856, with 452 fatalities,The global case fatality ratio looks only to the official tally of cases confirmed by the WHO. In southeast There have been a number of farming practices that have changed in response to outbreaks of the H5N1 virus, including: In one case, a boy with H5N1 experienced As of February 2008, the "median age of patients with influenza A (H5N1) virus infection is approximately 18 years [...] The overall case fatality proportion is 61% [...] Handling of sick or dead poultry during the week before the onset of illness is the most commonly recognized risk factor [...] The primary pathologic process that causes death is fulminant viral pneumonia. "H5N1 isolates are identified like this actual HPAI A(H5N1) example, Other examples include: A/duck/Hong Kong/308/78(H5N3), A/avian/NY/01(H5N2), A/chicken/Mexico/31381-3/94(H5N2), and A/As with other avian flu viruses, H5N1 has strains called "highly pathogenic" (HP) and "low-pathogenic" (LP). Our analysis showed several new findings. Webster speculates that substandard vaccines may be preventing the expression of the disease in the birds but not stopping them from carrying or transmitting the virus through feces, or the virus from mutating.In order to protect their poultry from death from H5N1, China reportedly made a vaccine based on reverse genetics produced with H5N1 antigens, that Dr Wendy Barclay, a virologist at the University of Reading believes have generated up to six variations of H5N1.Wild birds found to have been infected with HPAI were either sick or dead. First, all European, Middle Eastern, and African samples fall into a clade that is distinct from other contemporary Asian clades, all of which share common ancestry with the original 1997 Hong Kong strain.

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